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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3A
All Species:
16.36
Human Site:
S299
Identified Species:
36
UniProt:
O14802
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14802
NP_008986.2
1390
155641
S299
V
I
K
K
H
R
I
S
G
A
K
T
Q
M
I
Chimpanzee
Pan troglodytes
XP_507865
1349
150791
M264
I
S
G
A
K
T
Q
M
I
M
E
D
W
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536399
1390
155706
S299
V
I
K
K
H
R
I
S
G
A
K
T
Q
M
I
Cat
Felis silvestris
Mouse
Mus musculus
P08775
1970
217158
N296
Q
L
R
R
N
E
Q
N
G
A
A
A
H
V
I
Rat
Rattus norvegicus
O54889
1716
194174
P359
M
A
Q
E
Q
K
L
P
C
E
M
T
E
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514706
1382
154562
S291
V
I
K
K
H
R
I
S
G
A
K
T
Q
M
I
Chicken
Gallus gallus
Q5ZL98
1390
155685
S299
V
I
K
K
H
R
I
S
G
A
K
T
Q
M
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04052
1887
209150
S288
E
L
R
K
N
E
A
S
G
A
A
A
H
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P16356
1852
203961
N290
Q
L
Q
R
N
E
A
N
G
A
A
A
H
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P18616
1840
204671
G295
L
K
R
Q
E
K
N
G
A
P
A
H
I
I
S
Baker's Yeast
Sacchar. cerevisiae
P04051
1460
162283
K305
L
I
K
A
G
L
D
K
G
I
S
I
N
N
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
N.A.
98.8
N.A.
26
26.8
N.A.
95.9
96.2
N.A.
N.A.
N.A.
27.4
N.A.
27.8
N.A.
Protein Similarity:
100
96.6
N.A.
99.5
N.A.
40.8
43.9
N.A.
98.1
98.5
N.A.
N.A.
N.A.
43.1
N.A.
43.9
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
20
6.6
N.A.
100
100
N.A.
N.A.
N.A.
33.3
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
N.A.
100
N.A.
60
53.3
N.A.
100
100
N.A.
N.A.
N.A.
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
51.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
0
0
19
0
10
64
37
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% D
% Glu:
10
0
0
10
10
28
0
0
0
10
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
10
0
0
10
73
0
0
0
0
0
0
% G
% His:
0
0
0
0
37
0
0
0
0
0
0
10
28
0
0
% H
% Ile:
10
46
0
0
0
0
37
0
10
10
0
10
10
19
55
% I
% Lys:
0
10
46
46
10
19
0
10
0
0
37
0
0
0
0
% K
% Leu:
19
28
0
0
0
10
10
0
0
0
0
0
0
0
10
% L
% Met:
10
0
0
0
0
0
0
10
0
10
10
0
0
37
10
% M
% Asn:
0
0
0
0
28
0
10
19
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
19
0
19
10
10
0
19
0
0
0
0
0
37
0
0
% Q
% Arg:
0
0
28
19
0
37
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
46
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
46
0
0
10
% T
% Val:
37
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _